Gary F. Lewis, Ph.D.
Dr. Gary Lewis Contact Information:
Phone: (416) 340-4270
Fax: (416) 340-3314
Email: gary.lewis@uhn.ca
Webpage: http://www.uhnresearch.ca/researchers/profile.php?lookup=3448
Address: Toronto General Hospital
200 Elizabeth Str, EN12-244
Toronto, Ontario, Canada
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ACADEMIC STATUS
Departmental Status: Full Professor, Cross-Appointed

Primary/Cross-appointments: Primary: Medicine

Degrees: M.D., F.R.C.P.C.

Affiliations: Director, Banting and Best Centre, University of Toronto; Director, Division of Endocrinology and Metabolism, University of Toronto; Sun Life Financial Chair in Diabtes; Drucker Family Chair in Diabetes Research


RESEARCH
Research Divisions: Endocrine and Diabetes Platform

Research Interests:
1. Current Major Research Interests
The Lewis lab performs whole body, integrative, physiological studies in humans. The major line of research interest of Dr. Lewis' laboratory is: 

The Lewis lab has had a long interest in the mechanisms of various aspects of diabetic dyslipidemia, including postprandial lipemia, HDL lowering and hypertriglyceridemia. We have also had a long standing interest in the interaction between free fatty acids and pancreatic beta cell dysfunction. Previously we have performed both animal and human mechanistic studies but currently are focusing exclusively on the human. In 2002, working in close collaboration with Dr. Khosrow Adeli (U of T), we made the novel observation that the intestine, in addition to the liver, overproduces lipoproteins in insulin resistant states. In our current CIHR-funded work we are determining the mechanism of intestinal and hepatic lipoprotein overproduction in insulin resistance and Type 2 diabetes. We perform integrative, physiological studies in humans, attempting to determine the regulation of intestinal and hepatic lipoprotein particle production by hormones, nutrients and pharmacological agents.

Laboratory Personnel:

Research Assoc: Changting Xiao, PhD
Head Technician: Linda Szeto, MSc
Clinical Studies Co-ordinator/Nurse: Brenda Hughes, RN, Patricia Harley, RN, Kris Puzeris, RN

Postdoctoral Fellows:

Satya Dash
Cecilia Morgantini
Khajag Koulajian


SAMPLE PUBLICATIONS AND ABSTRACTS
Click on Link to PubMed