Jan 29, 2021

Professor Gramolini's Research Highlighted On American Journal of Physiology Podcast

Professor Gramolini observes a seated student's work on a computer.

Professor Gramolini observes a seated student's work on a computer.Congratulations to Professor Anthony Gramolini who was recently invited to appear on the AJP-Heart and Circulatory Physiology Podcast to discuss his lab's review, "Membrane proteomic profiling of the heart: past, present, and future."

Communicating his research in this type of virtual discussion was new to Professor Gramolini, but he quickly embraced the format.

"It was fun to discuss aspects of our work in that forum - how we approach things, and how to overcome some of the technical challenges in our work," Professor Gramolini said. "I think we all had a good time, and before we knew it was already over!"

Listeners interested in cardiac research are sure to have a good time, too. The podcast is facilitated by Professor Lisandra de Castro Brásand Professor Gramolini is also joined by Dr. Sarah Parker of Cedars Sinai, another expert in the field of proteomic profiling.

The major focus of the Gramolini Lab - and the research under discussion - is on identifying and studying specialized regions and gate-keeping membranes in cardiac muscle cells. The discussion on the podcast highlights the importance of basic science to the eventual development of effective treatments.

"The three of us discussed the limitations we have faced, how we have worked collaboratively with many labs, and the future of the field. There have been so many advances in technical abilities, equipment, and computer processing that we really see a lot of opportunities to expand our current understanding of the cardiac cell in the context of the whole heart, and what can happen in disease.

"We hope that having a thorough understanding of these membranes and what is in them will allow us to not only understand how various molecules are regulated in the cell, but how we might harness that information to provide therapies based on those principles."

Listen to the episode here.