Department of Physiology

Faculty Members

Associate Professor

Contact Info

T: (416) 946-5564
F: (416) 978-8532

Research Interests

Neurobiology of sleep and sleep disorders

Agostino Pierro

OBE, MD, FRCS(Eng.), FRCS(Ed), FAAP
Professor

Contact Info

T: (416) 813-7340
F: (416) 813-7477

Research Interests

Research is directed towards Neonatal Intestinal Disorders Requiring Surgery, including: Necrotizing enterocolitis (NEC), Acute Intestinal Injury, Stem Cells, Intestinal organoids and Randomized Controlled Trials (RCT)
Professor

Contact Info

T: (416) 813-6772
F: (416) 813-6775 x416

Research Interests

The aim of my research is to understand the fundamental biological and physiological mechanisms that direct lung development and the impact of preterm birth on this process.
Associate Professor

Contact Info

T: (416) 813-7654 309094
F: (416) 813-7717

Research Interests

Computational neuroscience (neural coding, dynamical systems theory, information theory), neuronal excitability, synaptic transmission, pain processing.
Assistant Professor

Contact Info

T: (416) 978-2509
F: (416) 978-6352 x416

Research Interests

Our lab studies NMDA receptors, focusing on their role in the pathophysiology of schizophrenia and the treatment of depression. Current projects in the lab examine the plasticity of neural circuits that are relevant to schizophrenia, and the changes in synaptic biochemistry and morphology that occur when NMDA receptors are dysfunctional.
Associate Professor

Contact Info

T: (416) 581-7839
F: (416) 581-7839

Research Interests

Molecular physiology of islet biology – metabolism, insulin secretion, and receptor tyrosine kinases.
Associate Professor

Contact Info

T: (416) 586-4800 4122
F: (416) 586-8588

Research Interests

The focus of my laboratory is the study of hematopoietic and mesenchymal stem cells.
Professor

Contact Info

T: (416) 813-5667
F: (416) 813-5252

Research Interests

Cellular and molecular mechanisms which control formation of the normal and malformed mammalian kidney; growth factor signaling; murine and organoid models of human kidney disease.
Professor

Contact Info

T: (416) 813-6272
F: (416) 813-7921

Research Interests

Purine and excitatory amino acid neurotransmitters in the spinal cord; synaptic transmission and plasticity in pain pathways.
Professor

Contact Info

T: (416) 340-5093

Mike Seed

MBBS, MRCPCH, FRCR
Associate Professor

Contact Info

T: (416) 813-6135

Research Interests

Relationship between cardiovascular physiology and brain development in the fetus and newborn
Professor

Contact Info

T: (416) 979-4900 14433
F: (416) 979-4936

Research Interests

Work in the lab ranges from molecular genotyping of human and rodent DNA samples to phenotyping pain in humans and rodent models of neuropathy, including pharmacology, immunohistochemistry, behaviour and electrophysiology.
Professor

Contact Info

T: (416) 946-3742
F: (416) 978-4940

Research Interests

Neural and non-neural mechanisms of oral-facial pain; mastication, swalling and related motor functions.
Assistant Professor

Contact Info

T: (416) 586-4800 8631/8258
F: (416) 586-5116

Research Interests

Research interests include mechanisms of Pelvic Organ Prolapse development, the role of ovarian hormones in the prevention of pelvic floor deterioration; use of urine-derived, patient-specific induced pluripotent stem cells for regeneration of urethral sphincter in women with Stress Urinary Incontinence.
Professor

Contact Info

T: (416) 603-5800 5107
F: (416) 603-5745

Research Interests

Mathematical modeling; Computational Neuroscience; Inhibitory cell models.
Professor

Contact Info

T: (416) 603-5131
F: (416) 603-5745

Research Interests

The mechanism of information transfer between neurons with particular focus on the function of the presynaptic nerve terminal. The direct examination of presynaptic ion channel activity and its relation to transmitter release.

Padmaja Subbarao

MD, MSc, FRCP(C)
Associate Professor

Contact Info

T: (416) 813-6167
F: (416) 813-6246

Research Interests

Asthma, epidemiology, intervention studies, infant pulmonary function, respiratory medicine
Professor

Contact Info

T: (416) 603-5077
F: (416) 603-5745

Research Interests

Control of presynaptic transmitter release. Mechanisms of exocytosis in neuronal and immune cells
Associate Professor

Contact Info

T: (416) 978-8848
F: (416) 978-3844

Research Interests

Our research interest is in studying the role of ion channels in neuroprotection against cerebral ischemia and stroke, and identifying potential therapeutic targets for stroke.
Associate Professor

Contact Info

T: (416) 813-5128

Research Interests

Sex hormone regulation of inflammation and susceptibility to Pseudomonas aeruginosa in cystic fibrosis (CF) airways. The impact on long-term respiratory risk of developmental deficiency of Lgl1.